Is Parkinson’s Disease Degenerative?

Most people believe that Parkinson’s disease is degenerative. Is this really true? The annual Parkinsons Recovery survey answers this very question. This program summarizes the findings.

The 2018 survey asks: have you been better, the same or worse since a year ago. Also discussed were therapies that were helpful.

Robert Rodgers PhD
Jump Start to Recovery
https://www.parkinsonsrecovery.com/jump-start-to-recovery
Road to Recovery from Parkinsons Disease

Craniosacral Therapy as Treatment for Parkinson’s Symptoms

Willem Visser is a craniosacral therapist from the Netherlands, currently living in Portland, OR, USA. When he was young, he witnessed two grandparents from both sides of family suffering with Parkinson’s disease. Finishing his study as a craniosacral therapist, he wrote a thesis on the work of biomedical engineer Aubrey de Grey.

De Grey is known for his view medical technology can prevent human beings from dying from aging, including Parkinson’s. Willem researched if and how craniosacral therapy could help with De Grey’s proposed strategies. And of course also how De Grey ideas could help PD’s. Willem later wrote about why craniosacral therapy can be of great benefit for Parkinson’s. Willem Visser practices and teaches Craniosacral Therapy and Reiki. He writes about craniosacral therapy for Parkinsons on his blog.

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery

Implications of Apoptosis for Symptoms of Parkinson’s Disease

John Rollins PhD discusses the critical role that is played by Apoptosis and why it has a critical influence on nervous system health. Apoptosis is the bodys natural process for repairing, regenerating and destroying damaged cells.

He discusses his longtime relationship with Dr. Bill McAnalley who was a recent guest on Parkinsons Recovery Radio and founder of Aroga.

Dr. Rollins explains how Aroga products and in particular the Core Pathways, Brain and Nerve Plus and Aloe 1 support and nurture neural tissue health.

https://arogalife.com/parkinsons-recovery

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery

Physical Therapy and Parkinson’s

Walter Mady discusses the importance of Physical Therapy for the Parkinson’s disease patient and the factors that have made the biggest difference in addressing his own Parkinson’s symptoms.

  • Walter Mady has been a Physical Therapist for 28 years in the private sector. Physical Therapists are healthcare specialists utilizing their knowledge of anatomy and physiology, therapeutic exercise, and ADL modifications when treating the Parkinson’s disease patient.
  • He specializes in manual therapy, orthopedic physical therapy, and is a specialist in exercise recreationally and therapeutically
  • Walter was diagnosed in 2008 with Parkinson’s Disease..
  • He discusses and stresses the importance of nutrition and exercise.

Walter Mady [wmady@comcast.net]

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery

Shifting the Parkinsons Disease Mindset

Dr. Hageseth dates his first non-motor symptoms to 2004 when his sense of smell disappeared. In 2008 he developed severe constipation which he has had ever since. In 2011 he saw the emergence of a tremor in his right hand which progressed over the following year to involve his entire right side. It went on to include stooped posture, shuffling gait, and problems with balance. A neurologist confirmed his diagnosis in 2012. He tried three different medications over the next four months but discontinued each one due to side effects or lack of efficacy.

His neurologist gave him one piece of advice: EXERCISE, EXERCISE, EXERCISE.

A year later many of his symptoms had regressed. He attributed his improvement to the intensity of his exercise and taking up yoga. He established his first website: Sweating Out Parkinsons Disease. He intended to encourage other PWPs to follow his example.

By 2014 he was doing so well that he had a DAT scan to confirm the diagnosis of PD. It was positive.

Over the last year and a half, he explored why more people are not doing better with PD. It was then that he started to examine how the mind may influence the course of PD. Exercise is the key to living a full life with PD, But if the mind does not believe the degree of improvement that exercise can achieve. Then improvement will only go so far.

Because of the problem of dyskinesia developing after five years on levodopa, he thinks newly diagnosed should pursue a program of great intensity and focus and manage their minds, so they realize they can live with PD and not require levodopa.

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery

Food Can Fix Things Drugs Cant

Click the arrow below to hear my interview with Bill McAnalley PhD who discusses why food can fix things that drugs cant. His discussion focuses on explaining the causes of Parkinson’s and the right foods to treat each cause.

Information about Dr. McAnalley’s company, is accessed by visiting  Aroga

Below are the talking points that Dr. McAnalley prepared for my interview with him on Parkinsons Recovery Radio where he explains why food can fix things drugs cant

Parkinson’s disease (PD), characterized with bradykinesia, static tremor, rigidity and disturbances in balance, is the second most common neuro-degenerative disorder. Alzheimer disease is first.

With the global trends in aging, the incidence of PD has increased year by year and the prevalence rate is up among the elderly over the age of 65 years. So far, there is still no exact cure for PD due to its diversity of etiology and complexity of symptoms.

Currently, Parkinson’s disease is treated with Levodopa and maybe Monamine, Oxidase Inhibitors (MOAs) or Acetylcholine inhibitors. Levodopa makes more Dopamine available for the dopamine receptor, MOAs increase the amount norepinephrine, dopamine and serotonin at their prospective receptors and acetylcholine inhibitors make more acetylcholine available to its receptor.

None of which address the physical cause of the disease.

The cause of PD has not been completely elucidated, but it has been generally acknowledged that the improvement of oxidative stress is one of the most important patho-physiological mechanisms.

Dr. Bill’s research has focused on stopping the causes of diseases like Parkinsons by:

  • The inhibition of oxidative stress:

PD patients are in a state of oxidative stress. Oxidative stress is caused by the increase of free radicals in the organism, while the ability to eliminate free radicals is decreased at the same time. A large amount of lipid peroxide, such as Malondialdehyde (MDA), hydroxyl, carbonyl, etc., will cause cell death, which leads to neuronal apoptosis ultimately.

The mitochondria is the power plant and energy conversion station of cells. It also regulates the process of gene expression and apoptosis. Recent reports have suggested that mitochondrial dysfunction is closely related to a variety of neuro-degenerative diseases including PD.

  • The reduction of toxic Excitatory Amino Acids (EAA): 

Glutamate (Glu), Also, gamma-aminobutyric acid (GABA) and enkephalin can can produce excitotoxicity effects on nerve cells. Glutamate creates an excitatory effect on nerve cells, and is toxic when Dopa Amine neurons are fully or partially degenerated.

  • The inhibition of neuroinflammation:

Neuroinflammation is a common and important pathological mechanism in nervous system diseases and different neurological diseases are involved in neuroinflammation at some stage. At present, it is believed that neuroinflammation was involved in an important cascade reaction in neuronal degeneration of PD.

When the central nervous system suffers from exogenous antigens stimulus, such as pathogenic microorganisms or foreign bodies, microglia will be rapidly activated. Then, the activated microglia cells can secrete various cytokines such as IL-1β, IL-2, IL-4, IL-6, TNF-α, and IFN-γ, etc. The cytokines cause is neuro-inflammation.

  • The inhibition of neuronal apoptosis:

Parkinsons is caused by the premature death of dopaminergic neurons by abnormal apoptosis activation. Energy for normal activities of brain cells comes directly from aerobic energy, and there is little energy storage. However once brain damage occurs, it will cause nerve cell apoptosis or death.

The Bcl-2 family of proteins regulate apoptosis. It is divided into two categories: anti-apoptosis gene (such as Bcl-2, Bcl-xL, Bcl-w, Bcl-1, etc.) and pro-apoptosis gene (such as Bax, Bak, Bad, Bid, etc.). Their ratio regulates apoptosis.

  • The inhibition of abnormal protein aggregation:

Misfolded and aggregated proteins play a key role in the pathogenesis of Parkinsons Disease. Protein aggregates differ from disease to disease. This common characteristic shows that protein deposition is toxic to neurons.

Studies confirmed that the activity of the proteasome dropped substantially in substantia nigra of patients with PD, which weakened the ability of the substantia nigra to degrade α-syn and other proteins.

  • Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration:

Nrf2 is a basic leucine zipper (bZIP) protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation. Several drugs that stimulate the NFE2L2 pathway are being studied for treatment of diseases that are caused by oxidative stress.

Listing of Core Food Ingredients that Address the Structure and Functional Causes of the Disease

  1. The inhibition of oxidative stress:

Brahmi, Bacopa monnieri

Maca root powder, Lepidium meyenii (Walp.)

Tongkat Ali (Longjack), Eurycoma Longifolia

Turmeric root powder, Curcuma longa

  1. The reduction of toxic Excitatory Amino Acids EAA:

Brahmi, Bacopa monnieri

  1. The inhibition of neuroinflammation:

Turmeric root powder, Curcuma longa

Wild Yam root, Dioscorea villosa

  1. The inhibition of neuronal apoptosis:

Noni Fruit, Morinda citrifolia

  1. The inhibition of abnormal protein aggregation:

Amia powder, Emblica officinalis

Turmeric root powder, Curcuma longa

  1. Targeting Nrf2 to Suppress Ferroptosis and

Mitochondrial Dysfunction in Neurodegeneration.

Chaga Mushroom, Inonotus Obliquus

Milk Thistle Seed Extract, Silybum marianum.

Tongkat Ali (Longjack), Eurycoma Longifolia

Aroga

Dr. Bill offered suggestions on the products he recommended for persons diagnosed with Parkinson’s. He recommended three
Aroga products: (1) the Core (2) the Plus Brain and Nerve and (3) the Bone, Joint and Endocrine (which supports hormones). At a minimum. the Core would take top priority.

Information about these products and the opportunity to order is available at:

https://arogalife.com/parkinsons-recovery

Sadly, Aroga products can only be shipped to locations in the United States.

Robert Rodgers PhD
Road to Recovery from Parkinsons Disease
https://www.parkinsonsdisease.me

References:

Front Pharmacol. 2017; 8: 634. The Mechanisms of Traditional Chinese Medicine Underlying the Prevention and Treatment of Parkinson’s Disease.

Front Neurosci. 2018 Jul 10;12:466. Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration.

More Ways to Fight Parkinson’s

How Natural Medicines Help Parkinson’s Disease. Barbara Frank uses Folk Medicine and Nature’s Medicines To Help Parkinson’s Patients. barbarafrank222.com

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery

High Dose Thiamine as a Novel, Promising Therapy

Parkinsons Recovery is dedicated to identifying promising new therapies that offer the promise of reversing symptoms of Parkinson’s disease. One such therapy, High-Dose Thiamine, was discussed on Parkinsons Recovery Radio by Italian neurologist Antonio Constantini MD. He has been prescribing High Dose Thiamine as a treatment for his Parkinson’s patients with good success. Click on the pointer to hear the replay.

Parkinsons disease (PD) is a systemic disease with motor and non-motor deficits. In July 2011, Dr. Costantini treated a 47-year-old man affected by spinocerebellar ataxia type 2 (SCA2). In this patient, fatigue as well as motor symptoms improved after parenteral high doses of thiamine (also this was our proprietary research).

He formulated the hypothesis that in some inherited and degenerative diseases of the nervous system, the pathogenesis of the symptoms could be linked to a focal thiamine deficiency due to a dysfunction of the circulation of thiamine in the intracellular space or to structural enzymatic abnormalities. He speculated this dysfunction could be responsive to high-dose thiamine. Parkinson’s disease has also been related to mutations associated with SCA2. Applying the same approach to patients with Parkinson’s symptoms the observed results were nothing short of startling and never previously described in literature.

Links: https://www.youtube.com/channel/UCwsHIcP_h6QVWwd4uRg-HDQ?view_as=subscriber

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery

 

Q&A About Aquas

Questions answered by Leonie Hibbert, a developer of the Aquas and asked by your host Robert Rodgers PhD, founder of Parkinsons Recovery:

  • How do I know I am dehydrated?
  • What are symptoms of dehydration?
  • I drink water all the time but I am still thirsty all the time. Why is this?
  • How can taking a few drops of Aquas every day help hydrate the body?
  • Would it help to increase the number of drops I take every day? Isn’t more better?
  • How did you determine what ingredients to include in the bottles?
  • If I am a man – can I take the female Aquas or vice versa?
  • If someone is very ill, can they take the Aquas and if so, how many drops should they take?
  • What are the side effects of detoxing from getting better hydration?
  • How do you know the Aquas work?
  • How long does a bottle last?
  • Why can’t I solve the problem of dehydration by simply drinking more water?
  • Why do so many people with Parkinson’s symptoms take Aquas?
  • Will Aquas help people with diabetes?
  • Why do you recommend a break of 2 days every week when taking the Aquas?
  • Are the Aquas FDA approved?
  • How do you know the Aquas are safe?
  • Who manufactures the Aquas?
  • Is a doctor’s prescription required for the Aquas?
  • Will the Aquas help with dry skin?
  • Do I have to take the Aquas with apple juice?
  • Is it ok to take the Aquas with breakfast?

For further information about the Aquas visit: https://www.aquas.us

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery

Sleep and Parkinson’s Disease

Now you may be able to prevent or reverse your Parkinson’s disease while you sleep…

Dr. Stasha Gominak MD received her medical degree from Baylor College of Medicine and completed her Neurology residency at the Massachusetts General Hospital in Boston.

From 2004 to 2016 she had a busy general neurology practice where she became fascinated with issues connected with sleep disorders. She published several pivotal articles about the global struggle with worsening sleep. Since 2016 she has divided her time between teaching the public about sleep and teaching clinicians the RightSleep© method of sleep repair.

Robert Rodgers PhD
Founder 2004
Parkinsons Recovery